Sharma, Sheeshpal ; Kumar, Pankaj ; Jaiswal, Anil ; Dube, Anuradha ; Gupta, Swati (2011) Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis Journal of Biomedical Nanotechnology, 7 (1). pp. 135-136. ISSN 1550-7033
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Official URL: http://www.ingentaconnect.com/content/asp/jbn/2011...
Related URL: http://dx.doi.org/10.1166/jbn.2011.1237
Abstract
Visceral leishmaniasis (VL) is the most severe of all the forms of leishmaniasis and usually lethal if untreated. The present work aimed to develop and characterize doxorubicin loaded mannan conjugated microparticles against experimental visceral leishmaniasis for selective and targeted delivery of doxorubicin to the macrophages of liver and spleen for the effective chemotherapy of VL. Macrophage targeting using doxorubicin loaded PLGA-microparticles would certainly improve the chemotherapy with reduced side effects against VL.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to American Scientific Publishers. |
| Keywords: | Doxorubicin; Microparticles; Targeting; Visceral Leishmaniasis |
| ID Code: | 101860 |
| Deposited On: | 11 Mar 2017 14:42 |
| Last Modified: | 11 Mar 2017 14:42 |
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