Chemoselective O-methylation of phenols under non-aqueous condition

Basak (née Nandi), Anindita ; Nayak, Mrinal K. ; Chakraborti, Asit K. (1998) Chemoselective O-methylation of phenols under non-aqueous condition Tetrahedron Letters, 39 (27). pp. 4883-4886. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(98)00885-5

Abstract

Chemoselective O-methylation of substituted phenols takes place in dry tetrahydrofuran (THF) in the presence of LiOH.H2O and dimethylsulfate (DMS). Quantitative methyl transfer from DMS preserves the atom economy.

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