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Kumar, Abhishek ; Waingankar, Tejashree Pradip ; D’Silva, Patrick (2024) Seahorse assay for the analysis of mitochondrial respiration using Saccharomyces cerevisiae as a model system Methods in Enzymology, 707 . pp. 673-683. ISSN 0076-6879

Prasad, Sanjay ; Nayak, Parth Sarathi ; D'Silva, Patrick (2024) A histidine-functionalized ROS scavenging hybrid nanozyme for therapeutic application in Parkinson's disease pathogenesis Materials Advances, 5 (6). pp. 2388-2399. ISSN 2633-5409

Susarla, Gautam ; Kataria, Priyanka ; Kundu, Amrita ; D'Silva, Patrick (2023) Saccharomyces cerevisiae DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins elife, 12 . ISSN 2050-084X

Pareek, Gautam ; Krishnamoorthy, Vivekanandhan ; D'Silva, Patrick (2023) Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocase Molecular and Cellular Biology, 33 (23). pp. 4641-4659. ISSN 0270-7306

Sinha, Devanjan ; Srivastava, Shubhi ; Krishna, Lekshmi ; D'Silva, Patrick (2023) Unraveling the intricate organization of mammalian mitochondrial presequence translocases: existence of multiple translocases for maintenance of mitochondrial function Molecular and Cellular Biology, 34 (10). pp. 1757-1775. ISSN 0270-7306

Matta, Srujan Kumar ; Pareek, Gautam ; Bankapalli, Kondalarao ; Oblesha, Anjaneya ; D'Silva, Patrick (2023) Role of Tim17 transmembrane regions in regulating the architecture of presequence translocase and mitochondrial DNA stability Molecular and Cellular Biology, 37 (6). ISSN 0270-7306

Kumar, Abhishek ; Waingankar, Tejashree Pradip ; D'Silva, Patrick (2023) Functional crosstalk between the TIM22 complex and YME1 machinery maintains mitochondrial proteostasis and integrity Journal of Cell Science, 136 (2). ISSN 0021-9533

Kumar, Abhishek ; Matta, Srujan Kumar ; Renganathan, Vigneshwaran ; D'Silva, Patrick (2022) A journey through the gateway of polytopic inner membrane proteins: the carrier translocase machinery Current Opinion in Physiology, 26 . p. 100533. ISSN 24688673

Vishwanathan, Vinaya ; D’Silva, Patrick (2022) Loss of function of mthsp70 chaperone variants leads to mitochondrial dysfunction in congenital sideroblastic anemia Frontiers in Cell and Developmental Biology, 10 . ISSN 2296-634X

Waingankar, Tejashree Pradip ; D'Silva, Patrick (2021) Multiple variants of the human presequence translocase motor subunit Magmas govern the mitochondrial import Journal of Biological Chemistry, 297 (6). p. 101349. ISSN 0021-9258

Katti, Prasanna ; Rai, Mamta ; Srivastava, Shubhi ; D'Silva, Patrick ; Nongthomba, Upendra (2021) Marf-mediated mitochondrial fusion is imperative for the development and functioning of indirect flight muscles (IFMs) in drosophila Experimental Cell Research, 399 (2). p. 112486. ISSN 0014-4827

Kumar, Abhishek ; Matta, Srujan Kumar ; D'Silva, Patrick (2020) Conserved regions of budding yeast Tim22 have a role in structural organization of the carrier translocase Journal of Cell Science, 133 (14). ISSN 0021-9533

Matta, Srujan Kumar ; Kumar, Abhishek ; D’Silva, Patrick ; Fox, Thomas (2020) Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit Molecular Biology of the Cell, 31 (11). pp. 1112-1123. ISSN 1059-1524

Bankapalli, Kondalarao ; Vishwanathan, Vinaya ; Susarla, Gautam ; Sunayana, Ningaraju ; Saladi, SreeDivya ; Peethambaram, Divya ; D'Silva, Patrick (2020) Redox-dependent regulation of mitochondrial dynamics by DJ-1 paralogs in Saccharomyces cerevisiae Redox Biology, 32 . p. 101451. ISSN 2213-2317

Srivastava, Shubhi ; Vishwanathan, Vinaya ; Birje, Abhijit ; Sinha, Devanjan ; D’Silva, Patrick (2019) Evolving paradigms on the interplay of mitochondrial Hsp70 chaperone system in cell survival and senescence Critical Reviews in Biochemistry and Molecular Biology, 54 (6). pp. 517-536. ISSN 1040-9238

Singh, Namrata ; Savanur, Mohammed Azharuddin ; Srivastava, Shubhi ; D'Silva, Patrick ; Mugesh, Govindasamy (2019) A manganese oxide nanozyme prevents the oxidative damage of biomolecules without affecting the endogenous antioxidant system Nanoscale, 11 (9). pp. 3855-3863. ISSN 2040-3364

Srivastava, Shubhi ; Savanur, Mohammad Azharuddin ; Sinha, Devanjan ; Birje, Abhijit ; R, Vigneshwaran ; Saha, Prasenjit Prasad ; D'Silva, Patrick (2017) Regulation of mitochondrial protein import by the nucleotide exchange factors GrpEL1 and GrpEL2 in human cells Journal of Biological Chemistry, 292 (44). pp. 18075-18090. ISSN 0021-9258

Singh, Namrata ; Savanur, Mohammed Azharuddin ; Srivastava, Shubhi ; D'Silva, Patrick ; Mugesh, Govindasamy (2017) A redox modulatory Mn₃O₄ Nanozyme with multi‐enzyme activity provides efficient cytoprotection to human cells in a Parkinson's disease model Angewandte Chemie, 129 (45). pp. 14455-14459. ISSN 00448249

Melvin, Prasad ; Bankapalli, Kondalarao ; D’Silva, Patrick ; Shivaprasad, P. V. (2017) Methylglyoxal detoxification by a DJ-1 family protein provides dual abiotic and biotic stress tolerance in transgenic plants Plant Molecular Biology, 94 (4-5). pp. 381-397. ISSN 0167-4412

Sinha, Devanjan ; Srivastava, Shubhi ; D'Silva, Patrick (2016) Functional diversity of human mitochondrial J-proteins is independent of their association with the inner membrane presequence translocase Journal of Biological Chemistry, 291 (33). pp. 17345-17359. ISSN 0021-9258

Saha, Prasenjit Prasad ; Srivastava, Shubhi ; Kumar S. K., Praveen ; Sinha, Devanjan ; D'Silva, Patrick (2015) Mapping key residues of ISD11 critical for NFS1-ISD11 subcomplex stability Journal of Biological Chemistry, 290 (43). pp. 25876-25890. ISSN 0021-9258

Roy, Bijan ; Ghosh, Aloke Kumar ; Srivastava, Shubhi ; D'Silva, Patrick ; Mukherjee, Partha Sarathi (2015) A Pd₈ tetrafacial molecular barrel as carrier for water insoluble fluorophore Journal of the American Chemical Society, 137 (37). pp. 11916-11919. ISSN 0002-7863

Bhowmick, Debasish ; Srivastava, Shubhi ; D'Silva, Patrick ; Mugesh, Govindasamy (2015) Highly efficient glutathione peroxidase and peroxiredoxin mimetics protect mammalian cells against oxidative damage Angewandte Chemie, 127 (29). pp. 8569-8573. ISSN 0044-8249

Vernekar, Amit A. ; Sinha, Devanjan ; Srivastava, Shubhi ; Paramasivam, Prasath U. ; D’Silva, Patrick ; Mugesh, Govindasamy (2014) An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires Nature Communications, 5 (1). ISSN 2041-1723

Srivastava, S ; Sinha, D ; Saha, P P ; Marthala, H ; D'Silva, Patrick (2014) Magmas functions as a ROS regulator and provides cytoprotection against oxidative stress-mediated damages Cell Death & Disease, 5 (8). e1394-e1394. ISSN 2041-4889

Samaddar, Madhuja ; Goswami, Arvind Vittal ; Purushotham, Jaya ; Hegde, Pushpa ; D'Silva, Patrick ; Fox, Thomas D. (2014) Role of the loop L_4,5 in allosteric regulation in mtHsp70s: in vivo significance of domain communication and its implications in protein translocation Molecular Biology of the Cell, 25 (14). pp. 2129-2142. ISSN 1059-1524

Sinha, D ; D'Silva, Patrick (2014) Chaperoning mitochondrial permeability transition: regulation of transition pore complex by a J-protein, DnaJC15 Cell Death & Disease, 5 (3). e1101-e1101. ISSN 2041-4889

Saha, Prasenjit Prasad ; Kumar, S.K.Praveen ; Srivastava, Shubhi ; Sinha, Devanjan ; Pareek, Gautam ; D'Silva, Patrick (2014) The presence of multiple cellular defects associated with a novel G50E Iron-Sulfur Cluster Scaffold protein (ISCU) mutation leads to development of mitochondrial myopathy Journal of Biological Chemistry, 289 (15). pp. 10359-10377. ISSN 0021-9258

Samaddar, Madhuja ; Goswami, Arvind Vittal ; Sinha, Devanjan ; Purushotham, Jaya ; D'Silva, Patrick (2014) Understanding the contribution of mtHsp70 towards mitochondrial dysfunction in Parkinson's disease: A yeast model Biophysical Journal, 106 (2). 186a. ISSN 0006-3495

R., Ratheesh Kumar ; N. S., Nagarajan ; S. P., Arunraj ; Sinha, Devanjan ; Veedin Rajan, Vinoth Babu ; Esthaki, Vinoth Kumar ; D’Silva, Patrick (2012) HSPIR: a manually annotated heat shock protein information resource Bioinformatics, 28 (21). pp. 2853-2855. ISSN 1367-4803

Goswami, Arvind Vittal ; Samaddar, Madhuja ; Sinha, Devanjan ; Purushotham, Jaya ; D'Silva, Patrick (2012) Enhanced J-protein interaction and compromised protein stability of mtHsp70 variants lead to mitochondrial dysfunction in Parkinson's disease Human Molecular Genetics, 21 (15). pp. 3317-3332. ISSN 0964-6906

Thakur, Anushikha ; Chitoor, Balasubramanyam ; Goswami, Arvind V. ; Pareek, Gautam ; Atreya, Hanudatta S. ; D'Silva, Patrick (2012) Structure and mechanistic insights into novel iron-mediated moonlighting functions of human J-protein cochaperone, Dph4 Journal of Biological Chemistry, 287 (16). pp. 13194-13205. ISSN 0021-9258

Pareek, Gautam ; Samaddar, Madhuja ; D'Silva, Patrick (2011) Primary sequence that determines the functional overlap between mitochondrial heat shock protein 70 Ssc1 and Ssc3 of Saccharomyces cerevisiae Journal of Biological Chemistry, 286 (21). pp. 19001-19013. ISSN 0021-9258

Krishnarjuna, B. ; Jaipuria, Garima ; Thakur, Anushikha ; D’Silva, Patrick ; Atreya, Hanudatta S. (2010) Amino acid selective unlabeling for sequence specific resonance assignments in proteins Journal of Biomolecular NMR, 49 (1). pp. 39-51. ISSN 0925-2738

Jaipuria, Garima ; Thakur, Anushikha ; D’Silva, Patrick ; Atreya, Hanudatta S. (2010) High-resolution methyl edited GFT NMR experiments for protein resonance assignments and structure determination Journal of Biomolecular NMR, 48 (3). pp. 137-145. ISSN 0925-2738

Goswami, Arvind Vittal ; Chittoor, Balasubramanyam ; D'Silva, Patrick (2010) Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components Journal of Biological Chemistry, 285 (25). pp. 19472-19482. ISSN 0021-9258

Sinha, D. ; Joshi, N. ; Chittoor, B. ; Samji, P. ; D'Silva, Patrick (2010) Role of Magmas in protein transport and human mitochondria biogenesis Human Molecular Genetics, 19 (7). pp. 1248-1262. ISSN 0964-6906

V. Rajan, Vinoth Babu ; D’Silva, Patrick (2009) Arabidopsis thaliana J-class heat shock proteins: cellular stress sensors Functional & Integrative Genomics, 9 (4). pp. 433-446. ISSN 1438-793X

D'Silva, Patrick R. ; Schilke, Brenda ; Hayashi, Masaya ; Craig, Elizabeth A. ; Brodsky, Jeffrey (2008) Interaction of the J-Protein Heterodimer Pam18/Pam16 of the mitochondrial import motor with the translocon of the inner membrane Molecular Biology of the Cell, 19 (1). pp. 424-432. ISSN 1059-1524

D'Silva, Patrick R. ; Schilke, Brenda ; Walter, William ; Craig, Elizabeth A. (2005) Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane Proceedings of the National Academy of Sciences of the United States of America, 102 (35). pp. 12419-12424. ISSN 0027-8424

Knieszner, Helena ; Schilke, Brenda ; Dutkiewicz, Rafal ; D'Silva, Patrick ; Cheng, Sara ; Ohlson, Maikke ; Craig, Elizabeth A. ; Marszalek, Jaroslaw (2005) Compensation for a defective interaction of the Hsp70 Ssq1 with the mitochondrial Fe-S cluster scaffold Isu Journal of Biological Chemistry, 280 (32). pp. 28966-28972. ISSN 0021-9258

D'Silva, Patrick ; Liu, Qinglian ; Walter, William ; Craig, Elizabeth A (2004) Regulated interactions of mtHsp70 with Tim44 at the translocon in the mitochondrial inner membrane Nature Structural & Molecular Biology, 11 (11). pp. 1084-1091. ISSN 1545-9993

D'Silva, Patrick D. ; Schilke, Brenda ; Walter, William ; Andrew, Amy ; Craig, Elizabeth A. (2003) J protein cochaperone of the mitochondrial inner membrane required for protein import into the mitochondrial matrix Proceedings of the National Academy of Sciences, 100 (24). pp. 13839-13844. ISSN 0027-8424

Liu, Qinglian ; D'Silva, Patrick ; Walter, William ; Marszalek, Jaroslaw ; Craig, Elizabeth A. (2003) Regulated cycling of mitochondrial Hsp70 at the protein import channel Science, 300 (5616). pp. 139-141. ISSN 0036-8075