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Number of items: 66.

Kavitha, C. V. ; Choudhary, Bibha ; Raghavan, Sathees C. ; Muniyappa, K. (2010) Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells Biochemical and Biophysical Research Communications, 399 (4). pp. 575-580. ISSN 0006-291X

Chandran, Anu V. ; Rajan Prabu, J. ; Manjunath, G. P. ; Neelakanteshwar Patil, K. ; Muniyappa, K. ; Vijayan, M. (2010) Crystallization and preliminary X-ray studies of the C-terminal domain of Mycobacterium tuberculosis LexA Acta Crystallographica Section F, 66 (9). pp. 1093-1095. ISSN 1744-3091

Khan, Krishnendu ; Vipin Madhavan, T. P. ; Muniyappa, K. (2010) Cloning, overexpression and purification of functionally active Saccharomyces cerevisiae Hop1 protein from Escherichia coli Protein Expression and Purification, 72 (1). pp. 42-47. ISSN 1046-5928

Singh, Pawan ; Neelakanteshwar Patil, K. ; Khanduja, Jasbeer Singh ; Sanjay Kumar, P. ; Williams, Alan ; Rossi, Franca ; Rizzi, Menico ; Davis, Elaine O. ; Muniyappa, K. (2010) Mycobacterium tuberculosis UvrD1 and UvrA proteins suppress DNA strand exchange promoted by cognate and noncognate RecA proteins Biochemistry, 49 (23). pp. 4872-4883. ISSN 0006-2960

Singh, Pawan ; Tripathi, Pankaj ; Muniyappa, K. (2010) Mutational analysis of active-site residues in the Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease: Asp122 and Asp193 are crucial to the double-stranded DNA cleavage activity whereas Asp218 is not Protein Science, 19 (1). pp. 111-123. ISSN 0961-8368

Sharadamma, N. ; Harshavardhana, Y. ; Singh, Pawan ; Muniyappa, K. (2010) Mycobacterium tuberculosis nucleoid-associated DNA-binding protein H-NS binds with high-affinity to the Holliday junction and inhibits strand exchange promoted by RecA protein Nucleic Acids Research, 38 (11). pp. 3555-3569. ISSN 0305-1048

Singh, Pawan ; Tripathi, Pankaj ; Silva, George H. ; Pingoud, Alfred ; Muniyappa, K. (2009) Characterization of Mycobacterium leprae RecA intein, a LAGLIDADG homing endonuclease, reveals a unique mode of DNA binding, helical distortion, and cleavage compared with a canonical LAGLIDADG homing endonuclease Journal of Biological Chemistry, 284 (38). pp. 25912-25928. ISSN 0021-9258

Rajan Prabu, J. ; Thamotharan, S. ; Khanduja, Jasbeer Singh ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2009) Crystallographic and modelling studies on Mycobacterium tuberculosis RuvA: additional role of RuvB-binding domain and inter species variability Biochimica et Biophysica Acta: Proteins & Proteomics, 1794 (7). pp. 1001-1009. ISSN 1570-9639

Kavitha, C. V. ; Nambiar, Mridula ; Ananda Kumar, C. S. ; Choudhary, Bibha ; Muniyappa, K. ; Rangappa, Kanchugarakoppal S. ; Raghavan, Sathees C. (2009) Novel derivatives of spirohydantoin induce growth inhibition followed by apoptosis in leukemia cells Biochemical Pharmacology, 77 (3). pp. 348-363. ISSN 0006-2952

Khanduja, Jasbeer Singh ; Tripathi, Pankaj ; Muniyappa, K. (2009) Mycobacterium tuberculosis RuvA induces two distinct types of structural distortions between the homologous and heterologous holliday junctions Biochemistry, 48 (1). pp. 27-40. ISSN 0006-2960

Rajan Prabu, J. ; Manjunath, G. P. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2008) Functionally important movements in RecA molecules and filaments: studies involving mutation and environmental changes Acta Crystallographica Section D, 64 (11). pp. 1146-1157. ISSN 0907-4449

Tripathi, Pankaj ; Pal, Debnath ; Muniyappa, K. (2007) Saccharomyces cerevisiae Hop1 protein zinc finger motif binds to the Holliday junction and distorts the DNA structure: implications for Holliday junction migration Biochemistry, 46 (44). pp. 12530-12542. ISSN 0006-2960

Ghosal, Gargi ; Muniyappa, K. (2007) The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity Journal of Molecular Biology, 372 (4). pp. 864-882. ISSN 0022-2836

Krishna, R. ; Rajan Prabu, J. ; Manjunath, G. P. ; Datta, S. ; Chandra, N. R. ; Muniyappa, K. ; Vijayan, M. (2007) Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA Journal of Molecular Biology, 367 (4). pp. 1130-1144. ISSN 0022-2836

Tripathi, Pankaj ; Anuradha, S. ; Ghosal, Gargi ; Muniyappa, K. (2006) Selective binding of meiosis-specific yeast Hop1 protein to the holliday junctions distorts the DNA structure and its implications for junction migration and resolution Journal of Molecular Biology, 364 (4). pp. 599-611. ISSN 0022-2836

Kim, Chang-Yub ; Rajan Prabu, J. ; Alipio, Emily Zabala ; Waldo, Geoffrey S. ; Thamotharan, S. ; Khanduja, Jasbeer Singh ; Lekin, Tim ; Hung, Li-Wei ; Yu, Minmin ; Terwilliger, Thomas C. ; Segelke, Brent ; Toppani, Dominique ; Bursey, Evan ; Muniyappa, K. ; Chandra, Nagasuma R. ; Vijayan, M. (2006) Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination Acta Crystallographica Section F, 62 (8). pp. 731-734. ISSN 1744-3091

Ghosal, Gargi ; Muniyappa, K. (2006) Hoogsteen base-pairing revisited: resolving a role in normal biological processes and human diseases Biochemical and Biophysical Research Communications, 343 (1). pp. 1-7. ISSN 0006-291X

Krishna, R. ; Manjunath, G. P. ; Kumar, P. ; Surolia, A. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2006) Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery Nucleic Acids Research, 34 (8). pp. 2186-2195. ISSN 0305-1048

Anuradha, S. ; Tripathi, Pankaj ; Mahajan, Kiran ; Muniyappa, K. (2005) Meiosis-specific yeast Hop1 protein promotes pairing of double-stranded DNA helices via G/C isochores Biochemical and Biophysical Research Communications, 336 (3). pp. 934-941. ISSN 0006-291X

Saikrishnan, K. ; Manjunath, G. P. ; Singh, Pawan ; Jeyakanthan, J. ; Dauter, Z. ; Sekar, K. ; Muniyappa, K. ; Vijayan, M. (2005) Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association Acta Crystallographica Section D: Biological Crystallography, 61 (8). pp. 1140-1148. ISSN 0907-4449

Anuradha, S. ; Muniyappa, K. (2005) Molecular aspects of meiotic chromosome synapsis and recombination Progress in Nucleic Acid Research and Molecular Biology, 79 . pp. 49-132. ISSN 0079-6603

Ghosal, Gargi ; Muniyappa, K. (2005) Saccharomyces cerevisiae Mre11 is a high-affinity G4 DNA-binding protein and a G-rich DNA-specific endonuclease: implications for replication of telomeric DNA Nucleic Acids Research, 33 (15). pp. 4692-4703. ISSN 0305-1048

Anuradha, S. ; Muniyappa, K. (2004) Saccharomyces cerevisiae Hop1 zinc finger motif is the minimal region required for its function in vitro Journal of Biological Chemistry, 279 (28). pp. 28961-28969. ISSN 0021-9258

Anuradha, S. ; Muniyappa, K. (2004) Meiosis-specific yeast Hop1 protein promotes synapsis of double-stranded DNA helices via the formation of guanine quartets Nucleic Acids Research, 32 (8). pp. 2378-2385. ISSN 0305-1048

Ganesh, N. ; Muniyappa, K. (2003) Mycobacterium smegmatis RecA protein is structurally similar to but functionally distinct from Mycobacterium tuberculosis RecA Proteins: Structure, Function, and Bioinformatics, 53 (1). pp. 6-17. ISSN 0887-3585

Ganesh, N. ; Muniyappa, K. (2003) Characterization of DNA strand transfer promoted by Mycobacterium smegmatis RecA reveals functional diversity with Mycobacterium tuberculosis RecA Biochemistry, 42 (23). pp. 7216-7225. ISSN 0006-2960

Datta, S. ; Ganesh, N. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2003) Structural studies on MtRecA-nucleotide complexes: insights into DNA and nucleotide binding and the structural signature of NTP recognition Proteins: Structure, Function, and Bioinformatics, 50 (3). pp. 478-485. ISSN 0887-3585

Guhan, N. ; Muniyappa, K. (2003) Mycobacterium tuberculosis RecA intein, a LAGLIDADG homing endonuclease, displays Mn2+ and DNA-dependent ATPase activity Nucleic Acids Research, 31 (14). pp. 4184-4191. ISSN 0305-1048

Guhan, N. ; Muniyappa, K. (2002) The RecA intein of Mycobacterium tuberculosis promotes cleavage of ectopic DNA sites implications for the dispersal of inteins in natural populations Journal of Biological Chemistry, 277 (43). pp. 40352-40361. ISSN 0021-9258

Venkatesh, R. ; Ganesh, N. ; Guhan, N. ; Sreedhar Reddy, M. ; Chandrasekhar, T. ; Muniyappa, K. (2002) RecX protein abrogates ATP hydrolysis and strand exchange promoted by RecA: insights into negative regulation of homologous recombination Proceedings of the National Academy of Sciences of the United States of America, 99 (19). pp. 12091-12096. ISSN 0027-8424

Guhan, N. ; Muniyappa, K. (2002) Mycobacterium tuberculosis RecA intein possesses a novel ATP-dependent site-specific double-stranded DNA endonuclease activity Journal of Biological Chemistry, 277 (18). pp. 16257-16264. ISSN 0021-9258

Reddy, Mothe Sreedhar ; Guhan, N. ; Muniyappa, K. (2001) Characterization of single-stranded DNA-binding proteins from mycobacteria the carboxyl-terminal domain of SSB is essential for stable association with its cognate RecA protein Journal of Biological Chemistry, 276 (49). pp. 45959-45968. ISSN 0021-9258

Bakshi, Rahul P. ; Galande, Sanjeev ; Muniyappa, K. (2001) Functional and regulatory characteristics of eukaryotic type II DNA topoisomerase Critical Reviews in Biochemistry & Molecular Biology, 36 (1). pp. 1-37. ISSN 1040-9238

Sreedhar Reddy, M. ; Vaze, Moreshwar B. ; Madhusudan, K. ; Muniyappa, K. (2000) Binding of SSB and RecA protein to DNA-containing stem loop structures: SSB ensures the polarity of RecA polymerization on single-stranded DNA Biochemistry, 39 (46). pp. 14250-14262. ISSN 0006-2960

Muniyappa, K. ; Anuradha, S. ; Byers, Breck (2000) Yeast meiosis-specific protein Hop1 binds to G4 DNA and promotes its formation Molecular and Cellular Biology, 20 (4). pp. 1361-1369. ISSN 0270-7306

Muniyappa, K. ; Vaze, M. B. ; Ganesh, N. ; Sreedhar Reddy, M. ; Guhan, N. ; Venkatesh, R. (2000) Comparative genomics of Mycobacterium tuberculosis and Escherichia coli for recombination (rec) genes Microbiology, 146 (9). pp. 2093-2095. ISSN 1350-0872

Datta, S. ; Prabu, M. M. ; Vaze, M. B. ; Ganesh, N. ; Chandra, Nagasuma R. ; Muniyappa, K. ; Vijayan, M. (2000) Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADP-AlF4: implications for decreased ATPase activity and molecular aggregation Nucleic Acids Research, 28 (24). pp. 4964-4973. ISSN 0305-1048

Vaze, Moreshwar B. ; Muniyappa, K. (1999) RecA protein of Mycobacterium tuberculosis possesses pH-dependent homologous DNA pairing and strand exchange activities: implications for allele exchange in mycobacteria Biochemistry, 38 (10). pp. 3175-3186. ISSN 0006-2960

Mary Kironmai, K. ; Muniyappa, K. ; Friedman, David B. ; Hollingsworth, Nancy M. ; Byers, Breck (1998) DNA-binding activities of Hop1 protein, a synaptonemal complex component from Saccharomyces cerevisiae Molecular and Cellular Biology, 18 (3). pp. 1424-1435. ISSN 0270-7306

Mary Kironmai, K. ; Muniyappa, K. (1997) Alteration of telomeric sequences and senescence caused by mutations in RAD50 of Saccharomyces cerevisiae Genes to Cells, 2 (7). pp. 443-455. ISSN 1356-9597

Galande, Sanjeev ; Muniyappa, K. (1997) Effects of nucleosomes and anti-tumor drugs on the catalytic activity of type II DNA topoisomerase from rat testis Biochemical Pharmacology, 53 (9). pp. 1229-1238. ISSN 0006-2952

Mythili, E. ; Anand Kumar, K. ; Muniyappa, K. (1996) Characterization of the DNA-binding domain of β protein, a component of phage λ Red-pathway, by UV catalyzed cross-linking Gene, 182 (1-2). pp. 81-87. ISSN 0378-1119

Galande, Sanjeev ; Muniyappa, K. (1996) Purification and functional characterization of type II DNA topoisomerase from rat testis and comparison with topoisomerase II from liver Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1308 (1). pp. 58-66. ISSN 0167-4781

Ajay Kumar, R. ; Vaze, Moreshwar B. ; Chandra, Nagasuma R. ; Vijayan, M. ; Muniyappa, K. (1996) Functional characterization of the precursor and spliced forms of RecA protein of Mycobacterium tuberculosis Biochemistry, 35 (6). pp. 1793-1802. ISSN 0006-2960

Ramdas, Jyoti ; Muniyappa, K. (1995) Recognition and alignment of homologous DNA sequences between minichromosomes and single-stranded DNA promoted by RecA protein Molecular and General Genetics MGG, 249 (3). pp. 336-348. ISSN 0026-8925

Kumar, K. A. ; Mahalakshmi, S. ; Muniyappa, K. (1993) DNA-induced conformational changes in RecA protein. Evidence for structural heterogeneity among nucleoprotein filaments and implications for homologous pairing Journal of Biological Chemistry, 268 (35). pp. 26162-26170. ISSN 0021-9258

Mythili, Y. ; Muniyappa, K. (1993) Formation of linear plasmid multimers promoted by the phage lambda Red-system in lon mutants of Escherichia coli Journal of General Microbiology, 139 (10). pp. 2387-2397. ISSN 0022-1287

Kumar, K. A. ; Muniyappa, K. (1992) Use of structure-directed DNA ligands to probe the binding of recA protein to narrow and wide grooves of DNA and on its ability to promote homologous pairing Journal of Biological Chemistry, 267 (34). pp. 24824-24832. ISSN 0021-9258

Rould, Elizabeth ; Muniyappa, K. ; Radding, Charles M. (1992) Unwinding of heterologous DNA by RecA protein during the search for homologous sequences Journal of Molecular Biology, 226 (1). pp. 127-139. ISSN 0022-2836

Muniyappa, K. ; Ramdas, J. ; Mythili, E. ; Galande, S. (1991) Homologous pairing between nucleosome cores on a linear duplex DNA and nucleoprotein filaments of RecA protein-single stranded DNA Biochimie, 73 (2-3). pp. 187-190. ISSN 0300-9084

Ramdas, J. ; Mythili, E. ; Muniyappa, K. (1991) Nucleosomes on linear duplex DNA allow homologous pairing but prevent strand exchange promoted by RecA protein Proceedings of the National Academy of Sciences of the United States of America, 88 (4). pp. 1344-1348. ISSN 0027-8424

Muniyappa, K. ; Williams, Kenneth ; Chase, John W. ; Radding, Charles M. (1990) Active nucleoprotein filaments of single-stranded binding protein and recA protein on single-stranded DNA have a regular repeating structure Nucleic Acids Research, 18 (13). pp. 3967-3973. ISSN 0305-1048

Ramdas, J. ; Mythili, E. ; Muniyappa, K. (1989) RecA protein promoted homologous pairing in vitro. Pairing between linear duplex DNA bound to HU Protein (nucleosome cores) and nucleoprotein filaments of recA protein-single-stranded DNA Journal of Biological Chemistry, 264 (29). pp. 17395-17400. ISSN 0021-9258

Muniyappa, K. ; Radding, C. M. (1986) The homologous recombination system of phage lambda. Pairing activities of beta protein Journal of Biological Chemistry, 261 (16). pp. 7472-7478. ISSN 0021-9258

Tsang, Siu Sing ; Muniyappa, K. ; Azhderian, Edward ; Gonda, David K. ; Radding, Charles M. ; Flory, John ; Chase, John W. (1985) Intermediates in homologous pairing promoted by recA protein: isolation and characterization of active presynaptic complexes Journal of Molecular Biology, 185 (2). pp. 295-309. ISSN 0022-2836

Flory, J. ; Tsang, S. S. ; Muniyappa, K. (1984) Isolation and visualization of active presynaptic filaments of recA protein and single-stranded DNA Proceedings of the National Academy of Sciences of the United States of America, 81 (22). pp. 7026-7030. ISSN 0027-8424

Muniyappa, K. ; Shaner, S. L. ; Tsang, S. S. ; Radding, C. M. (1984) Mechanism of the concerted action of recA protein and helix-destabilizing proteins in homologous recombination Proceedings of the National Academy of Sciences of the United States of America, 81 (9). pp. 2757-2761. ISSN 0027-8424

Ashkar, S. ; Muniyappa, K. ; Leibach, F. ; Mendicino, J. (1984) Evidence for a specific phosphoryl binding site in swine kidney phosphofructokinase Molecular and Cellular Biochemistry, 62 (1). pp. 77-92. ISSN 0300-8177

Flory, S. S. ; Tsang, J. ; Muniyappa, K. ; Bianchi, M. ; Gonda, D. ; Kahn, R. ; Azhderian, E. ; Egner, C. ; Shaner, S. ; Radding, C. M. (1984) Intermediates in homologous pairing promoted by RecA protein and correlations of recombination in vitro and in vivo Cold Spring Harbor Symposia on Quantitative Biology, 49 . pp. 513-523. ISSN 0091-7451

Muniyappa, K. ; Leibach, Fredrich H. ; Mendicino, Joseph (1983) Reciprocal regulation of fructose 1,6-bisphosphatase and phosphofructokinase by fructose 2,6-bisphosphate in swine kidney Life Sciences, 32 (3). pp. 271-278. ISSN 0024-3205

Muniyappa, K. ; Mendicino, Joseph (1983) Purification and properties of swine kidney phosphoprotein phosphatase Molecular and Cellular Biochemistry, 51 (2). pp. 177-189. ISSN 0300-8177

Mendicino, Joseph ; Muniyappa, K. ; Leibach, Fredrich H. (1982) [31] cAMP-dependent protein kinase, soluble and particulate, from swine kidney Methods in Enzymology, 90 . pp. 200-206. ISSN 0076-6879

Muniyappa, K. ; Leibach, Fredrich ; Mendicino, Joseph (1982) [68] Phosphoprotein phosphatase from swine kidney Methods in Enzymology, 90 . pp. 407-413. ISSN 0076-6879

Muniyappa, K. ; Adiga, P. Radhakantha (1980) Purification and properties of riboflavin-binding protein from the egg white of the duck (Anas platyrhynckos) Biochimica et Biophysica Acta (BBA)-Protein Structure, 623 (2). pp. 339-347. ISSN 0005-2795

Muniyappa, K. ; Adiga, P. R. (1980) Occurrence and functional importance of a riboflavin-carrier protein in the pregnant rat FEBS Letters, 110 (2). pp. 209-212. ISSN 0014-5793

Adiga, P. R. ; Muniyappa, K. (1978) Estrogen induction and functional importance of carrier proteins for riboflavin and thiamine in the rat during gestation Journal of Steroid Biochemistry, 9 (9). p. 829. ISSN 0022-4731

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