Self-assembling peptides: from molecules to nanobiomaterials

Adhikari, Bimalendu ; Banerjee, Arindam (2011) Self-assembling peptides: from molecules to nanobiomaterials Journal of the Indian Institute of Science, 91 . pp. 471-483. ISSN 0970-4140

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Abstract

Molecular self-assembly plays a vital role in the construction of various nanostructures using the 'bottom-up' approach. Peptides have been considered important bio-molecular building blocks for different nanoscale structures as they are biocompatible, biodegradable, generally non-toxic and can be attuned to environmental responses like pH, temperature, salt concentration and others. Peptide based nanostructures can offer various wonderful biological applications in tissue engineering, cell culture, regenerative medicine and drug delivery. In this review, the construction of short peptide-based different nanostructures including nanotubes, nanovesicles and nanofibers, short peptide-based nanoporous materials, short peptide-based nanofibrous hydrogels and nanovesicles for various biological applications has been discussed. Moreover, morphological transformations from one nanoscopic structure to an other type of nanostructure (e.g., nanotubes to nanovesicles).

Item Type:Article
Source:Copyright of this article belongs to Indian Institute of Science.
ID Code:99668
Deposited On:03 Nov 2016 09:31
Last Modified:03 Nov 2016 09:31

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