Fast and accurate quantification using genetic algorithm optimized 1H-13C refocused constant-time INEPT

Manu, V. S. ; Kumar, Anil (2013) Fast and accurate quantification using genetic algorithm optimized 1H-13C refocused constant-time INEPT Journal of Magnetic Resonance, 234 . pp. 106-111. ISSN 1090-7807

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.jmr.2013.06.013

Abstract

Using Genetic Algorithm, a global optimization method inspired by nature’s evolutionary process, we have improved the quantitative refocused constant-time INEPT experiment (Q-INEPT-CT) of Mäkelä et al. (JMR 204 (2010) 124–130) with various optimization constraints. The improved ‘average polarization transfer’ and ‘min–max difference’ of new delay sets effectively reduces the experimental time by a factor of two (compared with Q-INEPT-CT, Mäkelä et al.) without compromising on accuracy. We also discuss a quantitative spectral editing technique based on average polarization transfer.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Genetic Algorithm; Refocused-INEPT; Quantification; Spectral Simplification
ID Code:99367
Deposited On:12 Apr 2016 11:02
Last Modified:12 Apr 2016 11:03

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