Analysis of DNA sequences through segmentation: exploring the mosaic via statistical measures

Ramaswamy, Ramakrishna ; Azad, Rajeev K. (2003) Analysis of DNA sequences through segmentation: exploring the mosaic via statistical measures Physica Scripta, T106 . p. 21. ISSN 0031-8949

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Official URL: http://iopscience.iop.org/1402-4896/2003/T106/005/

Related URL: http://dx.doi.org/10.1238/Physica.Topical.106a00021

Abstract

The Jensen–Shannon divergence provides a quantitative entropic measure through which genomic DNA can be divided into compositionally distinct domains by a standard recursive segmentation procedure. In this article we show the scaling behaviour observed in domain length distribution and further explore the significance of these domains in the context of gene location, in application to the segmentation of a complete bacterial genome. We also show that this entropic measure has the potential of detecting the horizontally transferred genes in a genome.

Item Type:Article
Source:Copyright of this article belongs to Royal Swedish Academy of Sciences.
ID Code:98853
Deposited On:22 May 2015 12:11
Last Modified:22 May 2015 12:11

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