Evaluation of physicochemical properties, and antimicrobial efficacy of monoclinic sulfur-nanocolloid

Roy Choudhury, Samrat ; Mandal, Amrita ; Chakravorty, Dipankar ; Gopal, Madhuban ; Goswami, Arunava (2013) Evaluation of physicochemical properties, and antimicrobial efficacy of monoclinic sulfur-nanocolloid Journal of Nanoparticle Research, 15 (4). p. 1491. ISSN 1388-0764

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Official URL: http://link.springer.com/article/10.1007%2Fs11051-...

Related URL: http://dx.doi.org/10.1007/s11051-013-1491-y

Abstract

Stable nanocolloids of monoclinic sulfur (β-SNPs) were prepared through ‘water-in-oil microemulsion technique’ at room temperature after suitable modifications of the surface. The morphology (rod shaped; ~50 nm in diameter) and allotropic nature (monoclinic) of the SNPs were investigated with Transmission Electron Microscopy and X-ray Diffraction technique. The surface modification, colloidal stability, and surface topology of β-SNPs were evaluated with Fourier Transform Infrared Spectroscopy, zeta potential analysis, and Atomic Force Microscopy. Thermal decomposition pattern of these nanosized particles was determined by Thermo Gravimetric Analysis (TGA). β-SNPs-colloids expressed excellent antimicrobial activities against a series of fungal and bacterial isolates with prominent deformities at their surface. In contrast, insignificant cytotoxicity was achieved against the human derived hepatoma (HepG2) cell line upon treatment with β-SNPs. A simultaneous study was performed to determine the stock concentration of β-SNP-colloids using a novel high phase liquid chromatographic method. Cumulative results of this study hence, elucidate the stabilization of nanosized monoclinic sulfur at room temperature and their potential antimicrobial efficacy over micron-sized sulfur.

Item Type:Article
Source:Copyright of this article belongs to Springer-Verlag.
Keywords: Monoclinic Sulfur nanoparticles Nanocolloids Antimicrobial Cytotoxicity Biocompatibility
ID Code:97756
Deposited On:18 Sep 2013 06:41
Last Modified:18 Sep 2013 06:41

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