Brahmachari, Samir K. ; Mishra, Rakesh K. ; Bagga, Rajesh ; Ramesh, N. (1989) DNA duplex with the potential to change handedness after every half a turn Nucleic Acids Research, 17 (18). pp. 7273-7281. ISSN 0305-1048
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Official URL: http://nar.oxfordjournals.org/content/17/18/7273
Related URL: http://dx.doi.org/10.1093/nar/17.18.7273
Abstract
Polymorphic forms of the DNA duplex with long stretches of structural monotony are known. Several alternating purine-pyrimidine sequences have been shown to adopt left-handed Z-conformation. We report a DNA sequence d(CGCGCGATCGAT)n exhibiting alternating right-handed B and left-handed Z helical conformation after every half a turn. Further, this unusual conformation with change in handedness after every six base pairs was induced at physiological superhelical density.
Item Type: | Article |
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Source: | Copyright of this article belongs to Oxford University Press. |
ID Code: | 97056 |
Deposited On: | 22 Jan 2013 07:17 |
Last Modified: | 22 Jan 2013 07:17 |
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