Antigen presentation

Chaturvedi, U. C. ; Rizvi, Nigar ; Mathur, A. (1987) Antigen presentation Current Science, 56 (12). pp. 561-587. ISSN 0011-3891

PDF - Publisher Version

Official URL:


Antigen presentation is a critical step in the initiation of immune response. Many types of cells can serve this function but the macrophages are the principal cells. The antigen-presenting cells (APC) must express Ia antigens and most of them produce interleukin-1. Macrophages bind, endocytose, catabolize and then express the antigen on the surface in the context if Ia and present it to T and B lymphocytes. On the other hand, B-lymphocytes present the native antigen (without catabolism) in the context of Ia antigen to helper T cells. The nature of APC, their functions and factors modulating them have been discussed.

Item Type:Article
Source:Copyright of this article belongs to Current Science Association.
ID Code:96766
Deposited On:09 Jan 2013 06:24
Last Modified:19 May 2016 09:11

Repository Staff Only: item control page