In vitro studies on protein binding of rifampicin

Kalpagam, Polasa ; Krishnaswamy, K. (1987) In vitro studies on protein binding of rifampicin Indian Journal of Pharmacology, 19 (3). pp. 225-229. ISSN 0253-7613

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1. Protein binding of rifampicin to varying albumin concentrations was carried out in vitro. Effect on other antitubercular drugs on protein binding of rifampicin was also studied. 2. The results indicated that rifampicin binding was influenced by albumin concentration, suggesting that it was chiefly bound to albumin. 3. Presence of other antitubercular drugs along with rifampicin decreased the percentage of bound rifampicin.

Item Type:Article
Source:Copyright of this article belongs to Medknow Publications.
Keywords:Protein Binding of Drugs; Rifampicin
ID Code:96349
Deposited On:14 Dec 2012 07:08
Last Modified:19 May 2016 08:51

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