Effect of food restriction of benzo(a)pyrene binding to DNA in wistar rats

Jagadeesan, V. ; Krishnaswamy, K. (1989) Effect of food restriction of benzo(a)pyrene binding to DNA in wistar rats Toxicology, 56 (2). pp. 223-226. ISSN 0300-483X

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0300-483X(89)90135-2

Abstract

A study was carried out to assess the binding of the carcinogen benzo(a)pyrene to DNA in different tissues under in vivo and in vitro conditions in Wistar rats which have been subjected to different levels of food restriction. The results showed that there was a significant increase in the binding of benzo(a)pyrene to hepatic DNA in food restricted animals in in vivo experimentation although this was not observed under in vitro conditions. There was a decrease in binding to pulmonary DNA and no change for renal DNA.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Undernutrition; Benzo(a)Pyrene-DNA Binding
ID Code:96342
Deposited On:13 Dec 2012 10:45
Last Modified:13 Dec 2012 10:45

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