Swamy, Musti Johinadha ; Sweeley, Charles C. (1989) On the metabolism of GM3 ganglioside in cultured human foreskin fibroblasts Biochemical and Biophysical Research Communications, 162 (3). pp. 1188-1193. ISSN 0006-291X
Full text not available from this repository.
Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0006-291X(89)90799-7
Abstract
The metabolism of GM3 ganglioside in cultured human foreskin fibroblasts was investigated by labeling cultured cells with [1-3H]-galactose for 48 hours, followed by a 48 hour chase. More than 80% of the radioactivity associated with GM3 was found in the hexose portion of the carbohydrate chain, whereas approximately 12% of the radioactivity was observed in the sialic acid moiety. The hexose and sialic acid residues lost 42% and 53% of their initial radioactivity, respectively, during the chase period, indicating an active metabolism of these sugar residues of GM3 in growing cultures.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 95902 |
| Deposited On: | 07 Dec 2012 11:53 |
| Last Modified: | 07 Dec 2012 11:53 |
Repository Staff Only: item control page
