An expeditious synthesis of a (3S,4S,5R)-trihydroxyazepane

Dhavale, Dilip D. ; Chaudhari, Vinod D. ; Tilekar, Jayant N. (2003) An expeditious synthesis of a (3S,4S,5R)-trihydroxyazepane Tetrahedron Letters, 44 (39). pp. 7321-7323. ISSN 0040-4039

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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...

Related URL: http://dx.doi.org/10.1016/S0040-4039(03)01870-7 |

Abstract

A practical approach for the synthesis of the (2S,3S,4R)-trihydroxyazepane 1d has been reported. Starting from α-D-xylo-pentodialdose, readily available from D-glucose, the sequence involves Wittig olefination and reductive amination as key steps.

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ID Code:9574
Deposited On:02 Nov 2010 11:52
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