Immunoproliferative small intestinal disease: a frequently missed diagnosis

Puri, A. S. ; Kumar, M. ; Khan, E. M. ; Pandey, R. ; Aggarwal, R. ; Naik, S. ; Choudhuri, G. ; Naik, S. R. (1996) Immunoproliferative small intestinal disease: a frequently missed diagnosis Indian Journal of Gastroenterology, 15 (2). pp. 46-48. ISSN 0254-8860

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Immunoproliferative small intestinal disease (IPSID) is a poorly recognized cause of malabsorption syndrome in India. Clinicopathological features of five patients with IPSID seen over a two-year period are described. Our data suggest that IPSID is commonly misdiagnosed as intestinal tuberculosis due to lack of awareness and reluctance to obtain small bowel biopsies. Empirical institution of anti-tubercular chemotherapy not only leads to delayed diagnosis but also possibly alters the natural history of the disease, resulting in an intermediate phase of amelioration followed by a terminal phase of lymphomatous transformation. The disease is therefore usually diagnosed at an advanced stage and hence is associated with a relatively poor outcome.

Item Type:Article
Source:Copyright of this article belongs to Indian Society of Gastroenterology.
Keywords:Intestinal Lymphoma; Alpha Chain Disease; Malabsorption; Pyrexia; Tuberculosis
ID Code:94977
Deposited On:10 Oct 2012 06:34
Last Modified:10 Oct 2012 06:34

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