Sumathy, K. ; Jayalakshmi, R. ; Shivayogi, M. S. ; Balaram, Hemalatha (2000) Cloning and characterization of the Plasmodium falciparum adenylosuccinate synthetase gene Current Science, 78 (5). pp. 610-615. ISSN 0011-3891
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Abstract
The cloning and deduced amino acid sequence of Plasmodium falciparum adenylosuccinate synthetase (PfADSS) are reported. PfADSS exhibited 67% homology with the human enzyme. On expression in Escherichia coli, enzymatically active ADSS was produced as deduced by functional complementation analysis. The PfADSS activity was inhibited by hadacidin, a known competitive inhibitor of this enzyme. Nucleotide sequence data are available at GenBank under accession number AF095282.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Indian Academy of Sciences. |
| ID Code: | 94678 |
| Deposited On: | 18 Oct 2012 07:24 |
| Last Modified: | 19 May 2016 07:28 |
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