Berman, J. ; Bryceson, A. D. M. ; Croft, S. ; Engel, J. ; Gutteridge, W. ; Karbwang, J. ; Sindermann, H. ; Soto, J. ; Sundar, S. ; Urbina, J. A. (2006) Miltefosine: issues to be addressed in the future Transactions of the Royal Society of Tropical Medicine and Hygiene, 100 (1). S41-S44. ISSN 0035-9203
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.trstmh.2006.02.009
Abstract
Future issues that need to be addressed for miltefosine are efficacy against non-Indian visceral leishmaniasis, efficacy in HIV-coinfected patients, efficacy against the many forms of cutaneous and mucosal disease, effectiveness under clinical practice conditions, generation of drug resistance and the need to provide a second antileishmanial agent to protect against this disastrous event, and the ability to maintain reproductive contraceptive practices under routine clinical conditions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Visceral Leishmaniasis; Cutaneous Leishmaniasis; Mucosal leishmaniasis; Miltefosine; Resistance; Toxicity |
| ID Code: | 94549 |
| Deposited On: | 07 Oct 2013 10:32 |
| Last Modified: | 07 Oct 2013 10:32 |
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