Mass spectral study of etoposide

Vairamani , M. ; Suma , K. ; Kamal, A. ; Gayatri, N. L. (1996) Mass spectral study of etoposide Rapid Communications in Mass Spectrometry, 10 (7). pp. 817-820. ISSN 0951-4198

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/%28SICI...

Related URL: http://dx.doi.org/10.1002/(SICI)1097-0231(199605)10:7<817::AID-RCM562>3.0.CO;2-5

Abstract

The antitumour agent etoposide has been studied under electron impact, chemical ionization and liquid secondary ion mass spectral conditions. The major fragment ions are found to be due to the cleavage of C4–O, C4O–glycoside and C1–C'1 bonds. These fragmentation pathways are established by collision-induced dissociation and accurate mass measurement. Mass spectral studies of 4′-demethylepipodophyllotoxin, epipodophyllotoxin and their respective p-fluoroanilidine derivatives were also carried out.

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Deposited On:25 Jul 2012 07:46
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