Garg, U. C. ; Ganguly, N. K. ; Sharma, S. ; Bhatnagar, R. (1987) Brush border enzyme as markers for ascending pyelonephritis: active immunization with pilli FEMS Microbiology Letters, 43 (2). pp. 127-131. ISSN 0014-5793
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Abstract
Activities of renal brushborder membrane (BBM) enzymes, alkaline phosphatase, maltase and leucine aminopeptidase, were determined in control, pyelonephritic and immunized-infected rats. The activities of all enzymes decreased significantly (P < 0.05) in obstructed kidney while activities of alkaline phosphatase and leucine aminopeptidase increased significantly (P < 0.05) in unobstructed kidney in early stages of infection. The affinity constant (Km) of all enzymes remained unaltered in control and experimental groups. Significant differences (P < 0.05) in the activities of BBM enzymes of infected and immunized-infected animals suggested a protective role of activeimmunization with pili.
| Item Type: | Article |
|---|---|
| Keywords: | Ascending Pyelonephritis; Pili; Brushborder Membrane Enzyme; Active Immunization |
| ID Code: | 93456 |
| Deposited On: | 21 Jun 2012 11:30 |
| Last Modified: | 10 Jul 2012 05:40 |
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