Synthesis of β-O-glycosides using enol ether and imidate derived leaving groups: emphasis on the use of nitriles as a solvent

Vankar, Y. D. ; Vankar, P. S. ; Behrendt, M. ; Schmidt, R. R. (1991) Synthesis of β-O-glycosides using enol ether and imidate derived leaving groups: emphasis on the use of nitriles as a solvent Tetrahedron, 47 (48). pp. 9985-9992. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)96047-8

Abstract

Two new methods of β-glycoside synthesis using donors 2 and 3 that contain leaving groups derived from enol ether and imidates have been developed. Effect of nitriles as a solvent in directing mainly β-glycosidations has been compared with various methods reported in the literature. Effectiveness of leaving group at low temperatures and participation of nitriles in the formation of nitrilium-nitrile conjugate has been emphasized.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:93366
Deposited On:15 Jun 2012 13:24
Last Modified:15 Jun 2012 13:24

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