Solvent mediated centric/non-centric polymorph pairs of an indole derivative: subtle variation of C-HO hydrogen bonds and C-Hπ interactions

Choudhury, Angshuman R. ; Nagarajan, Kuppuswamy ; Guru Row, Tayur N. (2006) Solvent mediated centric/non-centric polymorph pairs of an indole derivative: subtle variation of C-HO hydrogen bonds and C-Hπ interactions CrystEngComm, 2008 (8). pp. 482-488. ISSN 1466-8033

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Official URL: http://pubs.rsc.org/en/content/articlelanding/2006...

Related URL: http://dx.doi.org/10.1039/B604118C

Abstract

Centric (P21/n) and non-centric (P21) polymorphic pairs of biologically active 1-(4-fluorophenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one crystallized from different solvents have been elucidated via single crystal and powder X-ray diffraction studies, morphological observations and calorimetric measurements. C-H...O hydrogen bonding and weak intermolecular C-H...π interactions generate distinct packing features in the two forms.

Item Type:Article
Source:Copyright of this article belongs to Royal Society of Chemistry.
ID Code:93212
Deposited On:13 Jun 2012 10:36
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