An improved procedure for the three-component synthesis of highly substituted pyridines using ionic liquid

Ranu, Brindaban C. ; Jana, Ranjan ; Sowmiah, S. (2007) An improved procedure for the three-component synthesis of highly substituted pyridines using ionic liquid Journal of Organic Chemistry, 72 (8). pp. 3152-3154. ISSN 0022-3263

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Official URL: http://pubs.acs.org/doi/abs/10.1021/jo070015g

Related URL: http://dx.doi.org/10.1021/jo070015g

Abstract

A basic ionic liquid, [bmIm]OH, efficiently promotes a one-pot, three-component condensation of aldehydes, malononitrile, and thiophenols to produce highly substituted pyridines in high yields at room temperature. This reaction does not involve any hazardous organic solvent and toxic catalyst. The ionic liquid is recovered and recycled for subsequent reactions.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:92844
Deposited On:05 Jun 2012 10:25
Last Modified:05 Jun 2012 10:25

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