Pancreatic beta cell function in tropical pancreatic diabetes

Mohan, V. ; Snehalatha, C. ; Ramachandran, A. ; Jayashree, R. ; Viswanathan , M. (1983) Pancreatic beta cell function in tropical pancreatic diabetes Metabolism, 32 (12). pp. 1091-1092. ISSN 0026-0495

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Individuals with tropical pancreatic diabetes (TPD) have features of malnutrition and insulin-dependent diabetes but do not exhibit ketosis on withdrawal of insulin. Fasting and postglucose C-peptide responses were assessed in TPD and compared with noninsulin-dependent (NIDDM), insulin-dependent (IDDM), and control groups, matched for body weight. The C-peptide concentrations were lower in TPD in comparison with the controls and NIDDM patients but were significantly higher than in classical IDDM. It is likely that the higher C-peptide is responsible for the ketosis resistance in these patients.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:92526
Deposited On:01 Jun 2012 11:49
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