Oxidative stress and the development of diabetic complications-antioxidants and lipid peroxidation in erythrocytes and cell membrane

Parthiban, Anusha ; Vijayalingam, Selvamani ; Radha Shanmugasundaram, K. ; Mohan, Rema (1995) Oxidative stress and the development of diabetic complications-antioxidants and lipid peroxidation in erythrocytes and cell membrane Cell Biology International, 19 (12). pp. 987-994. ISSN 1065-6995

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1006/cbir.1995.1040

Abstract

Erythrocytes isolated from 131 cases of Non-Insulin Dependent Diabetes Mellitus (NIDDM) were studied for lipid peroxidation, antioxidant defences, and the maximum peroxidisable substrate in the cell membrane. Antioxidant defences are lowered in NIDDM, followed by significant rise in lipid peroxidation products. However, in the erythrocyte membrane, the total polyunsaturated peroxidisable lipids are lower than in normal erythrocytes which may be a causative factor affecting the survival of the cells.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:92475
Deposited On:01 Jun 2012 12:12
Last Modified:01 Jun 2012 12:12

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