Balasubramanian, A. S. (2001) Amyloid beta peptide processing, insulin degrading enzyme and butyrylcholinesterase Neurochemical Research, 26 (4). pp. 453-456. ISSN 0364-3190
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Official URL: http://www.springerlink.com/content/j0661738136381...
Related URL: http://dx.doi.org/10.1023/A:1010967602362
Abstract
Amyloid beta peptide implicated in Alzheimers disease is cleaved by insulin degrading enzyme (IDE). Abnormal cholinesterases similar to butyrylcholinesterase (BChE) are found in Alzheimer brain. The similarities between IDE and BChE (which is known to have an arylacylamidase and a metallocarboxypeptidase-like activity) such as their zinc metalloenzyme nature, their localization in glia and their ability to bind amyloid peptide in Alzheimers disease raise interesting questions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Springer. |
| Keywords: | Alzheimers Disease; Amyloid Peptide; Insulin Degrading Enzyme; Butyrylcholinesterase |
| ID Code: | 91588 |
| Deposited On: | 22 May 2012 12:23 |
| Last Modified: | 22 May 2012 12:23 |
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