Steric and conformational effects on the photophysical and DNA binding properties of novel viologen linked tolylacridines

Eldho, Nadukkudy V. ; Joseph, Joshy ; Ramaiah, Danaboyina (2001) Steric and conformational effects on the photophysical and DNA binding properties of novel viologen linked tolylacridines Chemistry Letters, 30 (5). pp. 438-439. ISSN 0366-7022

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Official URL: https://www.jstage.jst.go.jp/article/cl/30/5/30_5_...

Related URL: http://dx.doi.org/10.1246/cl.2001.438

Abstract

Two novel water soluble tolylacridines having viologen at the para and ortho to the acridine chromophore have been synthesized. Photophysical and DNA binding studies have revealed that the para-isomer exists in the extended conformation and binds to DNA by partial intercalation whereas the ortho-isomer exists both in folded and extended conformations and fails to interact with DNA.

Item Type:Article
Source:Copyright of this article belongs to Chemical Society of Japan.
ID Code:90863
Deposited On:14 May 2012 13:59
Last Modified:14 May 2012 13:59

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