Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4

Ramaiah, Danaboyina ; Schuster, Gary B. ; Koch, Troels ; Henrikørum, (1998) Detection of thymine [2+2] photodimer repair in DNA: selective reaction of KMnO4 Nucleic Acids Research, 26 (17). pp. 3940-3943. ISSN 0305-1048

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Official URL: http://nar.oxfordjournals.org/content/26/17/3940.s...

Related URL: http://dx.doi.org/10.1093/nar/26.17.3940

Abstract

The specific reaction of potassium permanganate with thymine in single-stranded DNA was employed to analyze thymine [2+2] dimer repair in DNA and in DNA/peptide nucleic acid hybrid duplexes. This simple and highly sensitive chemical assay is convenient for monitoring repair of thymine dimers in oligonucleotides.

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Deposited On:14 May 2012 13:59
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