Chaturvedi, U. C. ; Shukla, M. I. ; Mathur, A. (1981) Thymus-dependent lymphocytes of dengue virus-infected mice spleens mediate suppression through prostaglandin Immunology, 42 (1). pp. 1-6. ISSN 0019-2805
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Official URL: http://www.interscience.wiley.com/jpages/0019-2805...
Abstract
Our earlier observations indicate that adoptive transfer of spleen cells obtained from dengue type 2 virus (DV)-primed mice suppressed DV antigen-specific antibody secretion as detected by Jerne PFC technique. Findings of this paper indicate that the suppression was produced by non-glass-adherent cells, macrophage-depleted (by carbonyl iron) cells and by T lymphocytes of the spleen but not by the glass-adherent cells and B lymphocytes. The activity of these cells is dependent upon production of prostaglandin as shown by abrogation of their suppressor activity by pre-treatment of cells by indomethacin or aspirin which are known to block synthesis of prostaglandins.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| ID Code: | 90684 |
| Deposited On: | 12 May 2012 05:00 |
| Last Modified: | 25 Jun 2012 10:19 |
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