Shukla, M. I. ; Chaturvedi, U. C. (1986) Presence of I-region gene products on the cells and their products of the dengue virus-induced suppressor pathway British Journal of Experimental Pathology, 67 (4). pp. 563-569. ISSN 0007-1021
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Abstract
We have studied both the cells and the suppressor factors of the dengue virus-induced suppressor pathway for the presence of I-region gene products. The suppressor activity of Ts1, Ts2 and Ts3 cells was abrogated by treatment with anti I-Jk or I-Ak anti-sera and complement. Both the suppressor factors were absorbed out by anti I-Jk and I-Ak immunosorbent columns. The activity of the suppressor factor was abolished by treatment with anti I-Jk antisera. Macrophage presentation of suppressor factor to precursors of Ts2 cells was abolished by treatment with anti I-Ak antisera and complement but not by anti I-Jk antisera. Thus I-region gene products were found throughout the dengue virus induced suppressor pathway.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Lewis, London. |
| ID Code: | 90651 |
| Deposited On: | 14 May 2012 05:41 |
| Last Modified: | 14 May 2012 05:41 |
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