CCR5 Δ 32 deletion and atopic asthma in India

Batra, J. ; Sharma, M. ; Chatterjee, R. ; Sharma, S. ; Mabalirajan, U. ; Ghosh, B. (2005) CCR5 Δ 32 deletion and atopic asthma in India Thorax, 60 . p. 85. ISSN 0040-6376

Full text not available from this repository.

Official URL:


Chemokine receptor 5 (CCR5) contributes to the generation of a Th1 immune response by interacting with agonists such as RANTES, MIP-1α , and MIP-1β .1 A 32 base pair deletion (Δ 32) in CCR5 has been proposed to protect individuals against HIV infection and to bias the immune system towards a Th2-driven response, thus affecting the susceptibility to develop allergic diseases such as asthma. In a study in Scottish children, Hall et al reported an association of CCR5Δ 32 with a reduced risk of asthma2 but found.

Item Type:Article
Source:Copyright of this article belongs to BMJ Publishing Group.
ID Code:89931
Deposited On:02 May 2012 13:28
Last Modified:02 May 2012 13:28

Repository Staff Only: item control page