Self-induced nystatin resistance in Dictyostelium discoideum

Kasbekar, D. P. ; Madigan, S. ; Katz, E. R. (1995) Self-induced nystatin resistance in Dictyostelium discoideum Anitmicrobial Agents and Chemotherapy, 27 (6). pp. 974-976. ISSN 0066-4804

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Official URL: http://aac.asm.org/content/27/6/974.short

Related URL: http://dx.doi.org/10.1128/?AAC.27.6.974

Abstract

The cellular slime mold Dictyostelium discoideum is normally susceptible to the action of the polyene antibiotic nystatin. We describe conditions under which transient nystatin resistance can be induced in the absence of detectable changes in sterol composition. These results suggest that nystatin plays a positive role in promoting resistance to itself.

Item Type:Article
Source:Copyright of this article belongs to American Society for Microbiology.
ID Code:89105
Deposited On:30 Mar 2012 10:08
Last Modified:30 Mar 2012 10:08

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