Tripathi Ravish, C. ; Pandey, Suresh K. ; Kar, K. ; Dikshit, M. ; Saxena, Anil K. (1999) Synthesis and SAR studies of 1-substituted-n-(4-alkoxycarbonypiperidin-1-yl)alkanes as potent antiarrhythmic agents Bioorganic & Medicinal Chemistry Letters, 9 (18). pp. 2693-2698. ISSN 0960-894X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0960-894X(99)00456-4
Abstract
Synthesis and SAR studies of the title compounds have resulted in the identification of structural and physicochemical parameter (Vw) contributing for antiarrhythmic activity. Among the two most promising compounds 3a & 3b, the 3a has shown antiarrhythmic activity comparable to quinidine.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 89093 |
| Deposited On: | 30 Mar 2012 10:32 |
| Last Modified: | 30 Mar 2012 10:32 |
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