In vitro and in vivo activity of a recombinant toxin, OLX-209, which targets the erbB-2 oncoprotein.

Fischer, P. H. ; Bird, R. E. ; Kasprzyk, P. G. ; King, C. R. ; Turner, N. A. ; Pastan, I. ; Kihara, A. ; Batra, J. (1994) In vitro and in vivo activity of a recombinant toxin, OLX-209, which targets the erbB-2 oncoprotein. Advances in Enzyme Regulation, 34 . pp. 119-128. ISSN 0065-2571

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0065-2571(94)90012-4

Abstract

OLX-209 has readily measurable activity, is safe in experimental animals, and is efficacious in model systems. These results support the concept of OLX-209 and provide groundwork for further development of this oncoprotein targeted agent.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:88895
Deposited On:30 Mar 2012 06:44
Last Modified:30 Mar 2012 06:44

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