A novel probe for human DNA fingerprinting based on chi-like sequences

Ehtesham, Nasreen Z. ; Das, Ashis ; Hasnain, Seyed E. (1992) A novel probe for human DNA fingerprinting based on chi-like sequences Gene, 111 (2). pp. 261-263. ISSN 0378-1119

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0378-1119(92)90697-N

Abstract

A synthetic oligodeoxyribonucleotide (oligo) containing crossover initiating hotspot-like sequences was designed on the assumption that hypervariability is partly due to the presence of molecular signals which promote recombination. This oligo, when used as a probe for human DNA fingerprinting, generated individual-specific DNA band patterns. The probability of two unrelated individuals having the same DNA band pattern, using this probe, was estimated to be 1.9 × 10-13.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Forensic Sciences; Genetic Polymorphism; Hypervariability; Recombination Signal
ID Code:88622
Deposited On:29 Mar 2012 09:26
Last Modified:29 Mar 2012 09:26

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