The Role of FSH and LH in the initiation of ovulation in rats and hamsters: A study using rabbit antisera to ovine FSH and LH

Jagannadha Rao, A. ; Moudgal, N. R. ; Madhwa Raj, H. G. ; Lipner, H. ; Greep, R. O. (1974) The Role of FSH and LH in the initiation of ovulation in rats and hamsters: A study using rabbit antisera to ovine FSH and LH Journal of Reproduction and Fertility, 37 . pp. 323-330. ISSN 0022-4251

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Official URL: http://www.reproduction-online.org/content/37/2/32...

Related URL: http://dx.doi.org/10.1530/jrf.0.0370323

Abstract

The relative rôles of FSH and LH in ovulation induction in immature and adult cycling rats and hamsters have been evaluated. Both heterologous purified pituitary hormones and homologous crude pituitary extracts have been used as ovulatory stimuli in immature animals primed with PMSG. Well-characterized FSH and LH antisera have been used in the above model systems to achieve specific neutralization of FSH and LH. The present study revealed that LH is the physiological trigger needed for induction of ovulation in both rats and hamsters and FSH cannot, by itself, induce ovulation in the total absence of LH.

Item Type:Article
Source:Copyright of this article belongs to Society for Reproduction and Fertility.
ID Code:88024
Deposited On:26 Mar 2012 14:00
Last Modified:26 Mar 2012 14:00

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