An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin

Kumar, Pradeep ; Pandey, Menaka ; Gupta, Priti ; Dhavale, Dilip D. (2010) An organocatalytic route to the synthesis of lactone moiety of compactin and mevinolin Tetrahedron Letters, 51 (44). pp. 5838-5839. ISSN 0040-4039

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.08.093

Abstract

An efficient synthesis of lactone moiety of compactin has been achieved. The stereogenic centers were generated by means of iterative proline-catalyzed sequential α-aminoxylation and Horner-Wadsworth-Emmons (HWE) olefination of aldehydes.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Lactone; Proline; Organocatalysis; Aminoxylation; Compactin
ID Code:87229
Deposited On:16 Mar 2012 06:14
Last Modified:19 Mar 2012 11:32

Repository Staff Only: item control page