Facile diketopiperazine formation from dipeptides containing α-aminoisobutyric acid. Conformational factors influencing cyclisation

Nagaraj, Ramakrishnan ; Balaram, Padmanabhan (1977) Facile diketopiperazine formation from dipeptides containing α-aminoisobutyric acid. Conformational factors influencing cyclisation Heterocycles, 7 (2). pp. 885-890. ISSN 0385-5414

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Abstract

Diketopiperazines were formed in good yields on deprotection of N-protected dipeptide esters containing a-aminoisobutyric acid residues. Cyclisation is likely to be favored by conformational constraints introduced by the gem dialkyl groups.

Item Type:Article
Source:Copyright of this article belongs to Japan Institute of Heterocyclic Chemistry.
ID Code:87148
Deposited On:16 Mar 2012 09:25
Last Modified:12 Jul 2012 09:26

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