13C Nuclear magnetic resonance spectroscopy in the elucidation of structures of diterpenoid alkaloids

Joshi, Balawant S. ; Wunderlich, John K. ; William Pelletier, S. (1987) 13C Nuclear magnetic resonance spectroscopy in the elucidation of structures of diterpenoid alkaloids Canadian Journal of Chemistry / Revue Canadienne de Chimie, 65 (1). pp. 99-103. ISSN 0008-4042

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Official URL: http://www.nrcresearchpress.com/doi/abs/10.1139/v8...

Related URL: http://dx.doi.org/10.1139/v87-016

Abstract

13C Nuclear magnetic resonance spectroscopy is an exceptionally useful tool for the structure determination of diterpenoid alkaloids. A detailed study of the 1H and 13C nmr spectra of aconitine and 3-deoxyaconitine has permitted definite assignments to all the carbon atoms of the molecule. Chemical shift revisions have been suggested for certain carbon atoms of the C19-diterpenoid alkaloids. Chemical examination of Aconitumcolumbianum Nutt. ssp. columbianum, A. forrestii Stapf, Delphiniumtatsienense Franch., and D. vestitum Wall, resulted in the isolation of several new C19-diterpenoid alkaloids. The structure derivation of those alkaloids was based mainly on 13C nmr spectroscopic evidence.

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