Stem Cell Pharmacogenomics

Bapat, S. A. ; Mishra, G. C. (2004) Stem Cell Pharmacogenomics Current Topics in Medicinal Chemistry, 4 (13). pp. 1369-1381. ISSN 1568-0266

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Therapeutic stem cell applications represent a newly evolving approach for the treatment of several genetic and degenerative diseases. The advent of pharmacogenomics too, holds promise for an individualized, optimal treatment regime for a large variety of medical conditions. A combination of the benefits of these two technologies creates a new niche in therapeutic medicine research viz. that of stem cell pharmacogenomics (SCP). The development of this approach requires the application of existing technologies in genomics, proteomics and bioinformatics to resolve the various issues involved in advancing the therapeutic applications of stem cell medicine. In this brief overview of the subject, we attempt to provide fresh insights into the exclusive niche of stem cell pharmacogenomics and discuss some of the priority issues that need to be targeted, based on the existing principles of pharmacogenomics, stem cell characteristics and transplantation medicine. Advances in these areas are imperative in realizing the dream of stem cell therapies contributing towards the improvisation of the quality of human life.

Item Type:Article
Source:Copyright of this article belongs to Bentham Science Publishers.
Keywords:Pharmacogenomics; Stem Cell Therapy; Target Genes; Host Factors; Stem Cell Reprogramming; Immunosuppressive Drugs
ID Code:86635
Deposited On:12 Mar 2012 13:51
Last Modified:12 Mar 2012 13:51

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