N-Isogramin and some related N-Mannich bases of indole

Swaminathan, Sambasiva ; Narasimhan, Krishnaiyer (1966) N-Isogramin and some related N-Mannich bases of indole Chemische Berichte, 99 (3). pp. 889-894. ISSN 0009-2940

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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/cber.19...

Related URL: http://dx.doi.org/10.1002/cber.19660990325


Isogramin N (N-dimethylaminomethyl-indole) and three other related N-Mannich bases of the indole side were relatively few 3-dialkyl-and 1,3-bis-dialkylamino-methyl indoles by Mannich reaction in the absence of acetic won Sure. N-Isogramin isomerized to Gramin under different conditions. Win Attempts to N-substituted indoles by normal alkylation of 2-methyl-cyclohexanedione (1.3) or acetamino-malonsure-dithylester with N-Isogramin or its methosulfate, instead, provided the isomeric 3-substituted indoles.

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