Kantam, M. L. ; Rajasekhar, C. V. ; Gopikrishna, G. ; Rajender Reddy, K. ; Choudary, B. M. (2006) Proline catalyzed two-component, three-component and self-asymmetric Mannich reactions promoted by ultrasonic conditions Tetrahedron letters, 47 (33). pp. 5965-5967. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.06.042
Abstract
The proline catalyzed two-component and three-component asymmetric Mannich reaction with hydroxyacetone and self-Mannich reaction with propanal were performed successfully under ultrasonic conditions in 1 h to afford Mannich products in 90-98% isolated yields and 81-99% ees with excellent diastereoselectivities.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Organo Catalysis; Mannich Reaction; Asymmetric Synthesis; Proline; Ultrasonic Conditions |
| ID Code: | 86042 |
| Deposited On: | 07 Mar 2012 13:47 |
| Last Modified: | 07 Mar 2012 13:47 |
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