Analysis of connectivity map: control to glutamate injured and phenobarbital treated neuronal network

Kamal, Hassan ; Kanhirodan, Rajan ; Srinivas, Kalyan V. ; Sikdar, Sujit K. (2010) Analysis of connectivity map: control to glutamate injured and phenobarbital treated neuronal network Applied Physics Letters, 96 (16). 163704_1-163704_3. ISSN 0003-6951

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Official URL: http://apl.aip.org/resource/1/applab/v96/i16/p1637...

Related URL: http://dx.doi.org/10.1063/1.3398025

Abstract

We study the responses of a cultured neural network when it is exposed to epileptogenesis glutamate injury causing epilepsy and subsequent treatment with phenobarbital by constructing connectivity map of neurons using correlation matrix. This study is particularly useful in understanding the pharmaceutical drug induced changes in the neuronal network properties with insights into changes at the systems biology level.

Item Type:Article
Source:Copyright of this article belongs to American Institute of Physics.
Keywords:Brain Models; Drugs; Medical Disorders; Neural Nets; Neurophysiology; Organic Compounds; Patient Treatment
ID Code:84753
Deposited On:27 Feb 2012 13:58
Last Modified:27 Feb 2012 13:58

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