Sharma, T. ; Das, B. C. (1986) Higher incidence of spontaneous sister-chromatid exchanges (SCEs) and X-ray-induced chromosome aberrations in peripheral blood lymphocytes during pregnancy Mutation Research Letters, 174 (1). pp. 27-33. ISSN 0165-7992
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/016579...
Related URL: http://dx.doi.org/10.1016/0165-7992(86)90073-4
Abstract
In vitro cultures of peripheral blood lymphocytes from human and muntjac (barking deer) females who were at an advanced stage of pregnancy (32-37 weeks pregnant women and 20-24 weeks pregnant muntjacs) showed an enhanced frequency of SCEs and X-ray-induced chromosome aberrations when compared with those of nonpregnant females. Lymphocyte cultures of nonpregnant females to which sex hormones progesterone, oestrogen and human chorionic gonadotropin (HCG) were added together exogenously also showed higher frequency of SCEs. The plausible reason(s) for such high incidence of SCEs during pregnancy is discussed.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 8464 |
| Deposited On: | 27 Oct 2010 06:29 |
| Last Modified: | 30 May 2011 08:22 |
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