Pathogenic vibrios in the natural aquatic environment

Abstract

In recent years, members belonging to the genus Vibrio of the family Vibrionaceae have acquired increasing importance because of the association of several of its members with human disease. The most feared of the Vibrio species is Vibrio cholerae, the causative agent of cholera, a devastating disease of global significance. Other important vibrios of medical importance are V. parahemolyticus, V. vulnificus, V. mimicus, and to a lesser extent V. fluvialis, V. furnissii, V. hollisae, and V. damsela. Recent studies have also implicated V. alginolyticus and V. metschnikovii in human disease, although their complete significance has not yet been established. The virulence of all medically important vibrios is aided by a variety of traits that help breach human defenses. In this review, we provide an overview of the environmental distribution of the pathogenic vibrios and the important virulence traits that enable them to cause disease.