Nair, V. ; Vinod, A. U. ; Ramesh, R. ; Menon, R. S. ; Varma, L. ; Mathew, S. ; Chiaroni, A. (2002) An efficient multicomponent reaction involving the interception of the zwitterionic intermediate between DMAD and isocyanides with some active methylene compounds Heterocycles, 58 (1). pp. 147-151. ISSN 0385-5414
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Official URL: http://www.heterocycles.jp/library/abstract.php?ar...
Related URL: http://dx.doi.org/10.3987/COM-02-S(M)62
Abstract
The 1:1 zwitterionic intermediate generated from dimethyl acetylenedicarboxylate and isocyanide is intercepted with 2-hydroxy-1,4-naphthoquinone, 4-hydroxycoumarin, 4-hydroxy-1-methylquinolinone, 4-hydroxy-6-methylpyrone, and 1-naphthol in one-pot to give novel pyran annulated heterocyclic systems in good yields.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Japan Institute of Heterocyclic Chemistry. |
| Keywords: | Multicomponent Reaction; Zwitterion; Isocyanide; Protic Nucleophile; Pyran Heterocycle |
| ID Code: | 84116 |
| Deposited On: | 24 Feb 2012 11:42 |
| Last Modified: | 24 Feb 2012 11:42 |
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