N-Heterocyclic carbene-catalyzed reaction of chalcones and enals via homoenolate: an efficient synthesis of 1,3,4-trisubstituted cyclopentenes

Nair, Vijay ; Vellalath, Sreekumar ; Poonoth, Manojkumar ; Suresh, Eringathodi (2006) N-Heterocyclic carbene-catalyzed reaction of chalcones and enals via homoenolate: an efficient synthesis of 1,3,4-trisubstituted cyclopentenes Journal of the American Chemical Society, 128 (27). pp. 8736-8737. ISSN 0002-7863

Full text not available from this repository.

Official URL: http://pubs.acs.org/doi/abs/10.1021/ja0625677

Related URL: http://dx.doi.org/10.1021/ja0625677

Abstract

Nucleophilic heterocyclic carbene-catalyzed cyclopentannulation of enals and chalcones via homoenolate has been observed for the first time. Serendipitously, the reaction lead to a very efficient synthesis of 3,4-trans-disubstituted-1-aryl cyclopentenes instead of the expected cyclopentanones. The strategy works well with thienylidene tetralone also, leading to the tricyclic cyclopentene derivative.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:84087
Deposited On:24 Feb 2012 06:15
Last Modified:24 Feb 2012 06:16

Repository Staff Only: item control page