Intestine-specific, oral delivery of captopril/montmorillonite: formulation and release kinetics

Madurai, Suguna L. ; Joseph, Stella W. ; Mandal, Asit B. ; Tsibouklis, John ; Reddy, Boreddy S. R. (2010) Intestine-specific, oral delivery of captopril/montmorillonite: formulation and release kinetics Nanoscale Research Letters, 6 (1). 15_1-15_8. ISSN 1931-7573

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Official URL: http://www.nanoscalereslett.com/content/6/1/15/abs...

Related URL: http://dx.doi.org/10.1007/s11671-010-9749-0

Abstract

The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14 %w/w and which exhibits near-zero-order release kinetics.

Item Type:Article
Source:Copyright of this article belongs to Springer-Verlag.
Keywords:Captopril Montmorillonite; Intercalation; Intestine-specific Controlled Release; Release Kinetics
ID Code:83870
Deposited On:23 Feb 2012 07:11
Last Modified:23 Feb 2012 07:11

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