pH Oscillations in cell suspensions of Dictyostelium discoideum: their relation to cyclic-AMP signals

Malchow, D. ; Nanjundiah, V. ; Gerisch, G. (1978) pH Oscillations in cell suspensions of Dictyostelium discoideum: their relation to cyclic-AMP signals Journal of Cell Science, 30 . pp. 319-330. ISSN 0021-9533

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Official URL: http://jcs.biologists.org/content/30/1/319.short

Abstract

Cells of Dictyostelium discoideum known to release cyclic AMP (cAMP) rhythmically in the form of pulses, change with the same period of about 8 min the pH of their medium. The pH is used here as an indicator to investigate the effect of externally added cAMP pulses on the oscillations. Both a temporary increase in amplitude and a permanent phase shift can be induced. The phase-response curve indicates that the period can be increased and decreased by rhythmic stimulation with cAMP pulses.

Item Type:Article
Source:Copyright of this article belongs to The Company of Biologists Ltd.
ID Code:83173
Deposited On:16 Feb 2012 12:17
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