Ghosh, A. R. ; Nair, G. B. ; Dutta, P. ; Pal, S. C. ; Sen, D. (1991) Acute diarrhoeal diseases in infants aged below six months in hospital in Calcutta, India: an aetiological study Transactions of the Royal Society of Tropical Medicine and Hygiene, 85 (6). pp. 796-798. ISSN 0035-9203
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In a prospective 2-year study, 218 infants aged less than 6 months admitted to a children's hospital in Calcutta with acute diarrhoea and 102 infants (control group) from the out-patient department of the same hospital with similar age, sex and socio-economic composition as the diarrhoea patients, were concurrently investigated for enteropathogenic agents in the faeces. Enteropathogenic Escherichia coli, enterotoxigenic E. coli, and enteroadherent E. coli constituted the 3 types of diarrhoeagenic E. coli most frequently (57.4%) detected in the faeces of diarrhoeic infants either as a sole pathogen or in association with other microorganisms. Other enteropathogens detected were rotavirus, Campylobacter jejuni, Salmonella typhimurium and Aeromonas hydrophila. The frequency of detection of various aetiological agents was 72%; in the remaining 28% an infectious aetiology could not be determined. The study suggests that diarrhoeagenic E. coli plays a major role in the causation of acute diarrhoea in infants aged under 6 months in Calcutta.
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