Epidemic isolates of Vibrio cholerae 0139 express antigenically distinct types of colonization pili

Sengupta, T. K. ; Sengupta, D. K. ; Balakrish Nair, G. ; Ghose, Asoke C. (1994) Epidemic isolates of Vibrio cholerae 0139 express antigenically distinct types of colonization pili FEMS Microbiology Letters, 118 (3). pp. 265-271. ISSN 1574-6968

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Official URL: http://onlinelibrary.wiley.com/doi/10.1111/j.1574-...

Related URL: http://dx.doi.org/10.1111/j.1574-6968.1994.tb06839.x

Abstract

Vibrio cholerae belonging to the recently described serogroup 0139, which are responsible for the current cholera epidemics in India and Bangladesh, were shown to express pilus-like structures partially cross-reacting with the toxin-coregulated pilus of V. cholerae strain (0395) belonging to the 01 serogroup and classical biotype. The 0139 pili were composed of 20 kDa subunit proteins which were antigenically related to the 20 kDa pilus protein of another diarrhoeagenic non-01 V. cholerae strain (serogroup 034) isolated earlier. The pili described in this study were found to be involved in the intestinal colonization process and, therefore, may contribute towards the virulence of the 0139 epidemic isolates.

Item Type:Article
Source:Copyright of this article belongs to John Wiley and Sons.
Keywords:Vibrio Cholerae 0139; Intestinal Colonization; Pilus Antigen
ID Code:80795
Deposited On:02 Feb 2012 04:02
Last Modified:02 Feb 2012 04:02

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